What is the first-line therapy for males with pedophilic disorder?

The first-line therapy for males with pedophilic disorder is medroxyprogesterone administered intramuscularly. This medication acts as an anti-androgen and has the effect of reducing testosterone levels, which can subsequently diminish sexual arousal and fantasies associated with pedophilic impulses. The approach is based on the understanding that reducing testosterone can lead to a decrease in the behaviors and urges that characterize this disorder.

Medroxyprogesterone is part of a broader treatment plan that may also include psychotherapy and behavioral interventions. The effectiveness of this medication has been established through various studies and clinical practices focused on treating paraphilic disorders, particularly when there is a high risk of offending behaviors.

Other options, such as bupropion, fluoxetine, and methylprednisolone, do not target the hormonal aspects of sexual arousal in the same way and are not considered effective first-line treatments for pedophilic disorder. Bupropion is an antidepressant that can be used for certain mood disorders and smoking cessation, while fluoxetine is an SSRI that may help with anxiety or depression but does not specifically address the underlying issues of pedophilia. Methylprednisolone, a corticosteroid, is used primarily for inflammatory conditions and not related